For people with Psoriasis
There exists no available clinical data on the benefits of E45 lotion on psoriatic lesions.
However, the product contains Medilan, a purified form of lanolin. Lanolin is a waxy substance obtained from the wool of sheep and sometimes called wool fat. A lanolin/olive oil emollient has been shown to reduce dermatitis in preterm infant when applied for 4 weeks (1).
Another study showed that pure lanolin applied twice daily for four weeks was effective in treating moderate to severe foot dryness (2).
It is important to notice that lanolin may cause contact allergy. However, Medilan does, as such, not cause contact allergies (3).
Furthermore, the products contains petrolatum and light liquid paraffin, which are known to prevent water evaporating from the skin surface. Water evaporation is increased in psoriatic lesions compared with normal skin (4).
- Pediatr Dermatol. 2008 Mar-Apr;25(2):174-8
- Cutis. 2003 Jan;71(1):78-82
- Br J Nurs. 2000 Jan 13-26;9(1):54-7
- Ann Dermatol. 2012 May; 24(2): 168–174
- [J Drugs Dermatol. 2011 May;10(5):531-7]