Lauromacrogols (Psoriasis)

In moisturisers, lauromacrogols are usually added because of their anti-itch properties. Besides the anti-itching property, lauromacrogols can also function as a local anaesthetic.

Level of evidence: C

HelloSkin’s experts were unable to find any scientific data or clinical trial regarding the use of lauromacrogols in psoriasis.

However, lauromacrogols have been shown to have a beneficial effect on symptoms often seen in patients with different forms of psoriasis. In people with dry and itchy scalp conditions, a leave-on combination product containing lauromacrogols applied to one half of the scalp 3 times per week for 4 weeks was shown to reduced itching1.

However, in another study where different types of itching were experimentally induced in human volunteers, the lauromacrogols were only found effective itch-reducers in some, but not other types of itching2.

Studies have also shown that lauromacrogols can inhibit the formation of new smaller blood vessels, which can reduce blood flow to a lesion, and therefore reduce redness of the skin as shown in lab models and controlled animal experiments3.

The concentration of an ingredient is important for its efficacy, and therefore products containing the same ingredient may not necessarily have the same effect as in the studies mentioned above.

Updated: July 2017

References

1Skin Pharmacol Physiol. 2013

2Exp Dermatol. 2014

3Eur Rev Med Pharmacol Sci. 2016