Kigelia Africana (Psoriasis)

Kigelia africana is a tree found in most of sub-Saharan Africa. The roots, bark and fruits of the tree have been used for centuries for reviving the skin in general1. Recent research has shown that it is very effective as a healing agent for skin diseases. The fruit extracts not only contain individual compounds which are well known for their medicinal qualities, but the blend of these components exhibit a remarkable blend to slow the growth of 'fast dividing' cells, as well as to provide an antibacterial against various microorganisms2.

What does the science say?

Level of evidence: C

HelloSkin’s experts were unable to find any clinical trials investigating the effect of Kigelia Africana Fruit Extract in people with psoriasis. However, one of its suggested bioactive substances is verminoside, which has been reported to have anti-inflammatory properties in immune cells in laboratory models2. Laboratory studies have also shown Kigelia africana extracts to have antibacterial activities against a range of test bacteria including Staphylococcus aureus3.

In psoriatic plaques, colonisation with the bacteria S. aureus may be increased4. One study reported that S. aureus was present in 15 of 25 of the psoriatic plaques that were investigated, of which one third of the bacteria was toxic, and that the disease severity was linked to a higher enterotoxin production5 (toxins produced in or affecting the intestines).

The concentration of an ingredient is important for its efficacy, and therefore products containing the same ingredient may not necessarily have the same effect as in the studies mentioned above. Updated: July. 2017

Updated: July. 2017

References

1J Ethnopharmacol. 2016

2J Nat Prod. 2005

3Adv Pharmacol Sci. 2013

4Eur J Clin Microbiol Infect Dis. 2016

5J Am Acad Dermatol. 2005