Hyaluronic Acid (Eczema)

Hyaluronic acid is found in the matrix surrounding the cells in most connective tissue, and is especially abundant in the skin, where it plays a protective, and structure-stabilizing role1. In moisturisers, hyaluronic acid is often used because of its strong water-binding properties (humectant). It is said that 1g of hyaluronic acid can bind up to 6 litres of water2.

Level of evidence: C

Some studies have shown benefits of applying a moisturiser containing hyaluronic acid in people with atopic dermatitis. In one study, adults were asked to apply either the test cream or a control three times per day for 50 days3. The results showed that the test cream was more efficient at improving the severity in people with mild-to-moderate atopic dermatitis.

In another study, the same test cream was tested in infants and children with mild-to-moderate atopic dermatitis. After applying the cream three times per day for 22 days, the test cream more efficiently reduced the eczema severity, and other symptoms such as itching4. The participants did not use other treatments during the test period in any of the studie

It should be mentioned that the moisturiser tested in both studies also contained other ingredients that are believed to benefit skin health. Therefore, the effects are not necessarily related to the content of hyaluronic acid alone.

The concentration of an ingredient is important for its efficacy, and therefore products containing the same ingredient may not necessarily have the same effect as in the studies mentioned above.

Updated: July 2017

References

1J Eur Acad Dermatol Venereol. 2005

2Clin Cosmet Investig Dermatol. 2013

3J Drugs Dermatol. 2006

4J Pediatr. 2008